Formulasi dan Evaluasi Gel dari Ekstrak Kulit Putih Semangka (Citrullus Lanatus [Thunb.] Matsum. & Nakai) sebagai Pelembap Kulit

Shafira Rizkiah (1) , Sari Defi Okzelia (2) , Agung Sofyan Efendi (3)
(1) Sekolah Tinggi Ilmu Kesehatan Bani Saleh,
(2) Sekolah Tinggi Ilmu Kesehatan Bani Saleh,
(3) PT Phytochemindo Reksa, Bogor
https://doi.org/10.53675/jsfar.v3i2.394
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Terbitan
Vol 9 No 2 (2021): SABDARIFFARMA
Telah diserahkan
2022-01-20
Diterbitkan
2022-02-15
PDF (Inggris)

Abstrak

Gel pelembap kulit dapat memberikan efek lembap pada kulit. Salah satu bahan alami yang dapat dibuat sediaan gel ialah kulit putih semangka (Citrullus lanatus [Thunb.] Matsum. & Nakai) karena banyak mengandung vitamin dan citrulline. Penelitian ini bertujuan membuat sediaan gel dari ekstrak kulit putih semangka sebagai pelembap kulit. Penelitian ini menggunakan metode Pretest-Posttest Control Group Design. Tahap-tahap penelitian yaitu pengumpulan sampel, ekstraksi, formulasi sediaan gel pelembap variasi konsentrasi (0%, 1%, 2%, dan 3%), evaluasi sediaan yang meliputi organoleptik, homogenitas, daya sebar, pH, viskositas, uji iritasi dan uji kelembapan kulit. Ekstrak kental kulit putih semangka berwarna cokelat dan tidak berbau. Hasil evaluasi menunjukkan bahwa seluruh formula memenuhi parameter sediaan yang baik dan tidak mengiritasi kulit. Hasil uji efektivitas kelembapan menggunakan alat skin moisture analyzer SD-320 selama 5 hari pada kulit lengan bagian dalam panelis menunjukkan bahwa terdapat perbedaan kelembapan kulit sebelum dan sesudah diberikan perlakuan. Persentase kenaikan kelembapan untuk F0, F1, F2, dan F3 berturut-turut adalah 8,93%, 11,52%, 10,77%  dan  17,47%. Sediaan gel dari ekstrak kulit putih semangka (Citrullus lanatus [Thunb.] Matsum. & Nakai) berpotensi sebagai pelembap kulit dan memenuhi standar parameter gel yang baik.

Penulis

Shafira Rizkiah
Sekolah Tinggi Ilmu Kesehatan Bani Saleh
Sari Defi Okzelia
Sekolah Tinggi Ilmu Kesehatan Bani Saleh
https://orcid.org/0000-0002-2980-6249 (tidak diautentikasi)
Agung Sofyan Efendi
PT Phytochemindo Reksa, Bogor

Cara Mengutip

Formulasi dan Evaluasi Gel dari Ekstrak Kulit Putih Semangka (Citrullus Lanatus [Thunb.] Matsum. & Nakai) sebagai Pelembap Kulit. (2022). Jurnal Sabdariffarma: Jurnal Ilmiah Farmasi, 9(2), 33-44. https://doi.org/10.53675/jsfar.v3i2.394

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Referensi

Achroni, K. (2012). Semua Rahasia Kulit Cantik & Sehat Ada Disini. Javalitera.

Augustia, V. A. S., Oktaviani, I. I., & Setyati, W. (2020). Anthocyanin dan Flavonoid Extracted from Watermelon Rind (Citrullus lanatus) with Two different Colors of Watermelon Flesh: Yellow and Red. Material Science Forum, 998, 261–265.

Elmitra. (2017). Dasar-dasar Farmasetika dan Sediaan Semi Solid (1st ed.). Deepublish..

Emma, S., Iskandarsyah, & Praptiwi. (2014). Evaluasi, Uji Stabilitas Fisik Dan Sineresis Sediaan Gel Yang Mengandung Minoksidil, Apigenin Dan Perasan Herba Seledri (Apium Graveolens L.). Buletin Penelitian Kesehatan, 42(2), 213–222.

Gustriani, N., Novitriani, K., & Mardiana, U. (2016). Penentuan Trayek pH Ekstrak Kubis Ungu (Brassica oleracea L) Sebagai Indikator Asam Basa Dengan Variasi Konsentrasi Pelarut Etanol. Jurnal Kesehatan Bakti Tunas Husada, 16.

Harborne. (1987). Metode Fitokimia, Penuntun Cara Modern Menganalisis Tumbuhan.

Kementrian kesehatan Republik Indonesia. (2017). Farmakope Herbal Indonesia Edisi 2 (2nd ed.).

Luginda, R. A., Sari, B. L., & Indriani, L. (2018). Pengaruh Variasi Konsentrasi Pelarut Etanol Terhadap Kadar Flavonoid Total Daun Beluntas (Pluchea indica (L.)Less) Dengam Metode Microwave – Assisted Extraction (MAE). Universitas Pakuan Bogor.

Masluhiya, S. A. ., Widodo, & Widyarti, S. (2016). Formulasi Masker Alami Berbahan Dasar Bengkoang Dan Jintan Hitam Untuk Mengurangi Kerutan Pada Wajah. Jurnal Care, 4(2), 22–24.

Melani, H. D., Purwanti, T., & Soeratri, W. (2005). Korelasi Kadar Propilenglikol Dalam Basis Dan Pelepasan Dietilammonium Diklofenak Dari Basis Gel Carbopol ETD 2020. Majalah Farmasi Airlangga, 5.

Moncrieff, G., Cork, M., Lawton, S., Kokiet, S., Daly, C., & Clark, C. (2013). Use of Emollients in Dry-skin Conditions: Consensus Statement.

Muthmainnah. (2017). Skrining Fitokimia Senyawa Metabolit Sekunder Dari Ekestrak Etanol Buah Delima (Punica granatum L.) Dengan Metode Uji Warna. Media Farmasi, 13.

Najib, A. (2018). Ekstraksi Senyawa Bahan Alam (1st ed.). Deepublish.

Ndruru, K., & Purnomo, D. S. (2018). Formulasi Sediaan Gel Dari Ekstrak Kulit Putih Semangka (Citrullus Lanatus SCHRAD) sebagai Masker Wajah. Jurnal Dunia Farmasi, 2, 121–127.

Okzelia, S.D., Hendrati, D., & Iljas, N. (2017). Isolasi dan Pemisahan Senyawa Alkaloid dari Buah Mahkota Dewa (Phaleria macrocarpa Boerl.) dengan Metode Kromatografi Cair. Journal of Nursing and Health, 1 (2), 1-7. https://doi.org/10.25099/stkbs.010209175.

Oseni, O. A., & Okoye, V. I. (2013). Studies of Phytochemical and Antioxidant properties of the fruit of watermelon (Citrullus lanatus).(Thunb.). J. Pharm. Biomed. Sci, 27(27), 508–514.

Perkins, P. V., & Collins, J. K. (2004). Flesh quality and lycopene stability of fresh-cut watermelon. Postharvest Biology and Technology, 31, 159–166.

Rahmawati, D. A., & Setiawan, I. (2019). The Formulation and Physical Stability Test Of Gel Fruit Strawberry Extract (Fragaria x ananassa Duch.). Journal of Nutraceuticals and Herbal Medicine, 2, 38–46.

Senja, R. Y., & Amelia, R. (2020). Formulasi Dan Uji Stabilitas Gel Ekstrak Etanol Daun Kemangi (Ocimum sanctum L.) Dengan Pembentuk Gel Carbopol 940 Konsenrasi 0.5% & 0.75% dan HPMC. Medimuh, 1, 45–54.

Slamet, S., Anggun, B. D., & Pambudi, D. B. (2020). Uji Stabilitas Fisik Formula Sediaan Gel Ekstrak Daun Kelor (Moringa OleiferaLamk.). Jurnal Ilmiah Kesehata, 13, 115–122.

Subaidah, W. A., Hajrin, W., & Juliantoni, H. (2020). Formulasi dan evaluasi sifat fisik lotion ekstrak etanol daun kemuning (Murraya paiculata (L) Jack) dan daun lidah buaya (Aloe vera Linn). Sasambo Journal of Pharmacy, 1(1), 12–24.

Sumbayak, A. R., & Diana, V. E. (2018). Formulasi Hand Body Lotion Ekstrak Etanol Kulit Buah Ssemangka. Jurnal Dunia Farmasi, 2, 70–76.

Voight, R. (1994). Buku Pengantar Teknologi Farmasi (S. N. (ed.); V). Universitas Gadjah Mada Press.

Winnipeg, K. N. (2008). Skin Moisturizers: Therapeutic Potential and Preventive Maintenance of Dry Skin.

Yanhendri, & Widya, S. Y. (2012). Berbagai Bentuk Sediaan Topikal dalam Dermatologi. Bagian Ilmu Kesehatan Kulit dan Kelamin Fakultas Kedokteran Universitas Andalas.

Yuniarsih, N., Akbar, F., Lenterani, I., & Farhamzah. (2020). Formulasi Dan Evaluasi Sifat Fisik Facial Wash Gel Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus) Dengan Geling Agent Carbopol. 5, 57–67.